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Our Stolen Future: Chapter summaries
DES or DDT binds with the estrogen receptor. It was once thought that hormone-receptor binding was very specific, like a lock and key. Research has ... with the receptor that normally binds testosterone, the androgen receptor. An important lesson from Gray's work is that hormone disruption is not limited to the estrogen system. Virtually every hormone-receptor interaction ...
www.ourstolenfuture.org

Our Stolen Future: A list of endocrine-disrupting compounds
Androgen Inhibits androgen binding to the androgen receptor, androgen-induced transcriptional activity, and androgen action in developing, pubertal and adult male rats. Kelce 1995 Dicofol (Kelthane) Estrogen Vinggaard et al. 1999 Dieldrin Estrogen Binds to estrogen receptor ...
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EHP: Volume 107, Number 11 November 1999
Research Articles A Yeast Screen System for Aromatase Inhibitors and Ligands for Androgen Receptor: Yeast Cells Transformed with Aromatase and Androgen Receptor Paul Mak, Fernando Dela Cruz, and Shiuan Chen [html] [pdf] P. 855 ...
ehponline.org

Population Council | Endocrinology and Reproductive Biology Seminar Series
Center Title: "Regulation of estrogen action in the primate reproductive tract with new-generation steroid receptor modulators" 20 March 2008 6th floor Conference Room 633, 12:00–1:00 pm Speaker ... 633, 12:00–1:00 pm Speaker: Dr. Chawnshang Chang University of Rochester Title: "The androgen receptor is a tumor suppressor and proliferator in prostate cancer" Print this page @ E-mail this ...
popcouncil.org

Gesundheitsrisiken
LE, Kemppainen JA, Wilson EM (1995) Persistent DDT metabolite p,p'-DDE is a potent androgen receptor antagonist. Nature, 375:581-585 Spök A, Hofer H, Valenta R, Kienzl-Plochberger K, Lehner ...
global2000.at

Endocrine Disrupting Pesticides: Friends of the Earth: Briefing
Peripubertal exposure to the antiandrogenic fungicide, vinclozolin, delays puberty, inhibits the development of androgen-dependent tissues, and alters androgen receptor functions in the male rat. Toxicology and Inustrial Health 15: 65-79 return ...
foe.co.uk

Environmental Health Perspectives: Volume 115, Number 6, June 2007
A. Nylander-French 894 [ Abstract ] [ Full ] [ PDF ] GENE EXPRESSION | Estradiol and Bisphenol A Stimulate Androgen Receptor and Estrogen Receptor Gene Expression in Fetal Mouse Prostate Mesenchyme Cells Catherine A. Richter, Julia A. Taylor ...
ehponline.org

Our Stolen Future: Antiandrogens
Antiandrogens An antiandrogen competes for androgen receptor binding and acts as an androgen receptor antagonist, i.e. blocking or interfering with the actions of androgen hormones. Androgens regulate ... masculinization and defeminization of female offspring. Male rats exposed to an anti-androgen during sexual differentiation in utero display reproductive malformations such as shortened anogenital ...
ourstolenfuture.org

Our Stolen Future: Gupta confirms low dose effects of bisphenol A
(DES and arochlor 1016, a PCB mixture, in addition to BPA) permanently increased androgen receptor (AR) binding activity of the prostate in adulthood. "This is the first demonstration that ... the presence and in the absence of testosterone, and that they also, in vitro, increased androgen-binding activity. This indicates that the impact of the chemicals is via direct action ...
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CISAB | Dale R. Sengelaub - Curriculum vitae
Encyclopedia of Cognitive Sciences. Hebbeler, S.L., Verhovshek, T., Sengelaub, D.R. NMDA receptor blockade inhibits estrogenic support of dendritic growth in a sexually dimorphic rat spinal nucleus. ... Kalkbrenner, A.E., Sengelaub, D.R. Development of altered motoneuron-to-muscle specificity in androgen-sensitive rat spinal nuclei. Mills, A.C., Sengelaub, D.R. Masculinization of motoneuron ...
indiana.edu