Results 1 - 4 from 4 for dose response curve in 0.116 sec.
Our Stolen Future: Non-monotonic dose response curves
In a non-monotonic dose response curve (NMDRC) , the shape of the dose response curve reverses as the level of contamination goes up. Some ... effects of octylphenol on the ramshorn snail Marisa cornuarietis reveal a strongly non-monotonic dose-response curve for OP's impact on eggs per female and spawning masses per female. ...
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Our Stolen Future: Low dose effects
In mathematical terms, the slope of the dose response curve changes sign. The presence of non-monotonic dose response curves in endocrine disruption means that many toxicological tests have ...
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Our Stolen Future: Endocrine disruption includes anti-estrogenic impacts
The dose response curve in estrous length is an inverted u-shaped curve, or non-monotonic dose response curve, reported in many low dose studies. Faqi and Chahoud ... Hydrocarbon Receptor (AHR/AHR nuclear translocator (ARNT) Heterodimer Interacts with Naturally Occurring Estrogen Response Element Molecular and Cellular Endocrinology 157(1-2): 105-19 TCDD (dioxin) ...
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Our Stolen Future: Bisphenol A may interfere with treatment for prostate cancer
What did they find? Wetherill et al. first observed a dramatic nonmonotonic dose-response relationship between bisphenol A exposure and proliferation of prostatic adenocarcinoma cells. Their experiments ... per billion). As shown in the figure below, the largest response to BPA was observed mid-way along the dose-response curve, at 1 nanomolar. As required, for a successful experiment, ...
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